The damage to a developing child’s brain caused by brain tumours and their treatment carries an immense burden - two thirds of those cured will be disabled for the rest of their lives. Our research addresses the need to diagnose tumours earlier, so that treatment will be more effective and side effects less severe. It also covers studies into the effects of different treatments on brain development and disability, with a view to minimising damage and developing interventions that can reduce the disability burden for survivors.
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GNEKOW, A.K., WALKER, D.A., KANDELS, D., SCHRAPPE, M., (et al) (2017) A European randomised controlled trial of the addition of etoposide to standard vincristine and carboplatin induction as part of an 18-month treatment programme for childhood (≤16 years) low grade glioma – A final report (2017) European Journal of Cancer
GUDRUNARDOTTIER, T., MORGAN, A.T., LUX, A.L., (et al), (2016), Consensus paper on post-operative pediatric cerebellar mutism syndrome: the Iceland Delphi results . Child's Nervous System. Jul;32(7):1195-203
WALKER, D., WILNE, S., GRUNDY, R., (et al). (2016) A new clinical guideline from the Royal College of Paediatrics and Child Health with a national awareness campaign accelerates brain tumor diagnosis in UK children - "headSmart: Be Brain Tumour Aware" Nero-Oncology. Mar;18(3):445-54
CHU, T.P.C., SHAH, A., WALKER, D., COLEMAN, M.P., (2015) Pattern of symptoms and signs of primary intracranial tumours in children and young adults: A record linkage study . Archives of Disease in Childhood. 100(12):1115-22