Medical outcomes

The Children’s Brain Tumour Research Centre (CBTRC) is dedicated to supporting young brain tumour sufferers and their families. From the moment a patient realises something is wrong, through diagnosis, treatment and recovery, our research is there – guiding and informing the work of healthcare professionals. An important part of our research includes the selection, validation and application of child health outcome measures. This work aims to enhance techniques for measuring relevant outcomes for children and young people involved in clinical trials of new therapies in brain tumours. In addition, the CBTRC is studying the impact of different types of rehabilitation after brain injury and other chronic illnesses in children and young people of all ages. Finally, a new programme of research has recently commenced in the CBTRC to investigate the impact of surgical and tumour injury to the cerebellum in young children. This work is being carried out with the Nottingham Toddler Lab, University of Nottingham and will analyse outcomes during development with patients recovering after tumour surgery.

Recent publications

Kombogiorgas D, Sgouros S, Walsh A, Hockley A, Stevens M, Grundy R, et al (2007). Outcome of children with posterior fossa medulloblastoma: a single institution experience over the decade 1994-2003. Childs Nervous System. 23(4):399-405.

Walker D. Adolescent CNS tumours: my brain has damaged my life. In: Eden T, Barr R, Bleyer A, editors (2005). Cancer and the Adolescent. Oxford: Blackwell Publishing.

Grundy R, Hutton C, Middleton H, Imeson J, Pritchard J, Kelsey A, et al (2004). Outcome of patients with stage III or inoperable WT treated on the second United Kingdom Children's Cancer Study Group (UKCCSG) study. Pediatic Blood Cancer. 42:311-9.