Our profiles
Position
Postdoctoral Research Fellow
School/Division
Human Development
Research interests
Ependymoma
Analysis of whole genome SNP copy number, methylation and gene expression data to identify genes involved in the pathogenesis of ependymoma as well as candidates with prognostic significance.
Functional analysis of identified candidates.
CNS PNET and Medulloblastoma
Functional analysis of the involvement of the WNT pathway in CNS PNET and medulloblastoma.
Gene expression array analysis of CNS PNET.
Recent publications
Rogers HA, Miller S, Lowe J, Brundler MA, Coye, B and Grundy RG (2009) An investigation of WNT pathway activation and association with survival in central nervous system primitive neuroectodermal tumours (CNS PNET). Br J Cancer; 100(8): 1292-302
Rogers HA, Miller S, Lowe J, Ball G, Coyle B, and Grundy RG (2010) Gene expression analysis of central nervous system primitive neuroectodermal tumours identifies a subgroup associated with the WNT pathway and YAP1 (manuscript in preparation)
Miller S, Rogers HA, Rand V, Hayden J, Clifford S, Adamowicz-Brice M, Dyer S, Brundler M, Lowe J, Coyle B, Grundy RG (2010) Genome-wide molecular characterisation of central nervous system central nervous system primitive neuroectodermal tumour and prineoblastoma (manuscript in preparation)