About Us

aboutus2The Children’s Brain Tumour Research Centre (CBTRC) was established in 1997 at The University of Nottingham. It brings together a multidisciplinary team of healthcare professionals and researchers. The aim of the centre is to improve the understanding, treatment and outcomes of children and young adults who develop brain tumours.

The CBTRC has around 40 core staff, including both University and NHS researchers. We're dedicated to helping children who are diagnosed with brain tumours, both now and in the future.

Major projects

  • Ependymoma research. We've invested over £1.5 million since 2013 in ependymoma research including the flagship SIOP Ependymoma II Clinial trial
  • Glioblastoma investigation. We're leading teams to tackle the most aggressive and common malignant brain and central nervous system tumour
  • Children's Brain Tumour Drug Delivery Consortium. The CBTDDC brings together experts fro maround the world to work out new ways to deliver drugs through the blood-brain barrier
  • HeadSmart. This multi-award-winning campaign focuses on raising awareness of brain tumours, and is accredited by the NHS

Our history

CBTRC is established as part of the University's Golden Jubilee Development Campaign and is led by Professor David Walker​.

Receives funding for the Pathways Project (later known as The HeadSmart Campaign)​. 

Dr Beth Coyle joins the Centre as an independent research fellow. She leads a programme of work developing accurate tumour models in order to circumvent drug resistance and invasion/ metastasis in ependymomas and medulloblastomas and is promoted to an Associate Professor in 2005.

Professor Richard Grundy appointed as Professor of Paediatric Neuro Oncology & Cancer Biology, 
Department of Health commits to supporting the Pathways Project​.
Low Grade Astrocytoma in Early Life international translational research workshop – hosted and sponsored by CTBRC and PLGA​.
CBTRC achieves it’s 100th research publication .
HeadSmart campaign launched in association with The Brain Tumour Charity.

Dr Ruman Rahman promoted to Asssistant Professor in Molecular Neuro-Oncology,having begun his research career with CBTRC in 2007. He leads teams researching drug delivery and the biology of brain tumours.

Dr Stuart Smith is appointed as Clinical Associate Professor in Neurosurgey, having undertaken his PhD with Professor Grundy. His programme of work examines the effects of microRNAs on angiogenesis and tumour growth

CBTRC hosted and sponsored a Europe-wide Optic Pathway Glioma workshop.
CBTRC hosted the annual BNOS Conference “Neuro Oncology across the ages”​.
CBTRC launches the UK arm of a major, new European Trial and research study, called Biomeca. Funded by CRUK and Children with Cancer, it comprises research groups in the UK, Germany, France and Italy. ​
CBTRC hosted an international Cerebellar Mutism Syndrome risk assessment consensus and validation workshop​.
CBTRC launches the International Children’s Brian Tumour Drug Delivery Consortium​.
CBTRC exceeds £10m in research grant income.